Compare

Protagonist Therapeutics, Inc vs Septerna, Inc. vs Cumberland Pharmaceuticals Inc vs Xilio Therapeutics, Inc.

Latest annual figures from SEC filings. Each company is shown for its own most recent fiscal year, so period ends can differ. Select a figure to see its full history.

Latest fiscal yearProtagonist Therapeutics, Inc
PTGX
Septerna, Inc.
SEPN
Cumberland Pharmaceuticals Inc
CPIX
Xilio Therapeutics, Inc.
XLO
Year ended2025-12-312025-12-312025-12-312025-12-31
Revenue$46.02M$45.95M$44.52M$43.77M
Revenue growth (YoY)-89.4%n/m+17.6%+589.9%
Gross marginn/an/a85.0% (computed)n/a
Operating margin-343.6%-148.6%-6.3%-95.9%
Net margin-282.8%-106.4%-6.4%-80.1%
Net income-$130.15M-$48.88M-$2.84M-$35.04M
EPS (Diluted)-$2.05-$1.10-$0.19-$4.19
Operating cash flow$57.67M$110.19M$4.93M-$4.99M
Free cash flow$56.08M$109.67M$4.83M-$5.51M
Cash & equivalents$128.39M$120.72M$11.44M$137.53M
Total assets$668.19M$596.19M$76.82M$154.69M
Total liabilities$53.48M$214.26M$52.28M$119.41M
Shareholders' equity$614.71M$381.93M$24.88M$35.27M
Return on year-end equity-21.2%-12.8%-11.4%-99.3%
Shares outstanding62.58M44.81M14.96M4.53M

n/a means the company did not report that line under the concept TickerFacts maps, not that it is zero.

Revenue, most recent five fiscal years

Fiscal yearProtagonist Therapeutics, IncSepterna, Inc.Cumberland Pharmaceuticals IncXilio Therapeutics, Inc.
Latest$46.02M
Ended 2025-12-31
$45.95M
Ended 2025-12-31
$44.52M
Ended 2025-12-31
$43.77M
Ended 2025-12-31
1 year earlier$434.43M
Ended 2024-12-31
$1.07M
Ended 2024-12-31
$37.87M
Ended 2024-12-31
$6.34M
Ended 2024-12-31
2 years earlier$60.00M
Ended 2023-12-31
$151.0K
Ended 2023-12-31
$39.55M
Ended 2023-12-31
n/a
3 years earlier$26.58M
Ended 2022-12-31
n/a$42.01M
Ended 2022-12-31
n/a
4 years earlier$27.36M
Ended 2021-12-31
n/a$35.05M
Ended 2021-12-31
n/a