Septerna, Inc. (SEPN): Operating Income

Annual figures by period end, from SEC filings.

-$68.30M

Year ended 2025-12-31

-$43.55M

Trailing 12 months to 2026-06-30

2023-12-31 Operating Income (USD) 2025-12-31

Period ended	Operating Income	Change YoY	Source filing
2025-12-31	-$68.30M	n/m	2026-03-09, From 2025-01-01
2024-12-31	-$80.82M	n/m	2026-03-09, From 2024-01-01
2023-12-31	$2.08M	n/a	2025-03-27, From 2023-01-01

Operating Income at similar companies

Companies with the same SEC industry code (Pharmaceutical Preparations), reporting in the same currency, closest in revenue. Each shows its own latest fiscal year, so period ends differ.

Company	Year ended	Operating Income	Change YoY
Septerna, Inc. (SEPN)	2025-12-31	-$68.30M	n/m
Protagonist Therapeutics, Inc (PTGX)	2025-12-31	-$158.13M	n/m
Aquestive Therapeutics, Inc. (AQST)	2025-12-31	-$71.05M	n/m
Cumberland Pharmaceuticals Inc (CPIX)	2025-12-31	-$2.79M	n/m
Xilio Therapeutics, Inc. (XLO)	2025-12-31	-$41.98M	n/m
Gossamer Bio, Inc. (GOSS)	2025-12-31	-$170.73M	n/m
Wave Life Sciences, Inc. (WVE)	2025-12-31	-$215.38M	n/m
Lexicon Pharmaceuticals, Inc. (LXRX)	2025-12-31	-$48.91M	n/m
Biofrontera Inc. (BFRI)	2025-12-31	-$11.35M	n/m

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