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Ionis Pharmaceuticals Inc vs Madrigal Pharmaceuticals, Inc. vs Harmony Biosciences Holdings, Inc. vs Prestige Consumer Healthcare Inc.

Latest annual figures from SEC filings. Each company is shown for its own most recent fiscal year, so period ends can differ. Select a figure to see its full history.

Latest fiscal yearIonis Pharmaceuticals Inc
IONS		Madrigal Pharmaceuticals, Inc.
MDGL		Harmony Biosciences Holdings, Inc.
HRMY		Prestige Consumer Healthcare Inc.
PBH
Year ended2025-12-312025-12-312025-12-312026-03-31
Revenue$943.71M$958.40M$868.45M$1.09B
Revenue growth (YoY)+33.8%+432.1%+21.5%-4.3%
Gross marginn/an/a77.2%54.7%
Operating margin-40.4%-31.3%24.0%28.4%
Net margin-40.4%-30.1%18.3%17.5%
Net income-$381.39M-$288.28M$158.69M$190.30M
EPS (Diluted)-$2.38-$12.85$2.71$3.91
Operating cash flow-$268.58M-$189.55M$348.20M$257.63M
Free cash flow-$320.03M-$190.02M$347.89M$246.45M
Cash & equivalents$372.26M$198.69M$752.50M$63.87M
Total assets$3.52B$1.26B$1.27B$3.49B
Total liabilities$3.03B$656.90M$401.41M$1.61B
Shareholders' equity$489.09M$602.69M$870.22M$1.89B
Return on year-end equity-78.0%-47.8%18.2%10.1%
Shares outstanding163.30M22.84M57.73Mn/a

n/a means the company did not report that line under the concept TickerFacts maps, not that it is zero.

Revenue, most recent five fiscal years

Fiscal yearIonis Pharmaceuticals IncMadrigal Pharmaceuticals, Inc.Harmony Biosciences Holdings, Inc.Prestige Consumer Healthcare Inc.
Latest$943.71M
Ended 2025-12-31		$958.40M
Ended 2025-12-31		$868.45M
Ended 2025-12-31		$1.09B
Ended 2026-03-31
1 year earlier$705.14M
Ended 2024-12-31		$180.13M
Ended 2024-12-31		$714.73M
Ended 2024-12-31		$1.14B
Ended 2025-03-31
2 years earlier$787.65M
Ended 2023-12-31		$0
Ended 2023-12-31		$582.02M
Ended 2023-12-31		$1.13B
Ended 2024-03-31
3 years earlier$587.37M
Ended 2022-12-31		$0
Ended 2022-12-31		$437.86M
Ended 2022-12-31		$1.13B
Ended 2023-03-31
4 years earlier$810.46M
Ended 2021-12-31		$0
Ended 2021-12-31		$305.44M
Ended 2021-12-31		$1.09B
Ended 2022-03-31