IONIS PHARMACEUTICALS INC (IONS) › Operating IncomeIONIS PHARMACEUTICALS INC (IONS) — Operating IncomeAnnual figures by fiscal year, from SEC filings.2008: -$13.06M2009: -$27.54M2010: -$48.36M2011: -$71.10M2012: -$68.92M2013: -$51.67M2014: -$47.73M2015: -$75.76M2016: -$20.16M2017: $31.05M2018: -$61.37M2019: $365.88M2020: -$172.08M2021: -$30.19M2022: -$410.19M2023: -$353.73M2024: -$475.08M2025: -$381.68M-$381.68M2008Operating Income (USD)2025Fiscal YearOperating IncomeChange YoY2025-$381.68M+19.7%2024-$475.08M-34.3%2023-$353.73M+13.8%2022-$410.19M-1258.9%2021-$30.19M+82.5%2020-$172.08M-147.0%2019$365.88M+696.2%2018-$61.37M-297.7%2017$31.05M+254.0%2016-$20.16M+73.4%2015-$75.76M-58.7%2014-$47.73M+7.6%2013-$51.67M+25.0%2012-$68.92M+3.1%2011-$71.10M-47.0%2010-$48.36M-75.6%2009-$27.54M-110.9%2008-$13.06M—Other metrics: RevenueCost of RevenueGross ProfitNet IncomeEPS (Diluted)Total AssetsTotal LiabilitiesShareholders' EquityCash & EquivalentsOperating Cash FlowCapital ExpendituresShares OutstandingDividends Per Share