IONIS PHARMACEUTICALS INC (IONS) › Operating Cash FlowIONIS PHARMACEUTICALS INC (IONS) — Operating Cash FlowAnnual figures by fiscal year, from SEC filings.2008: $212.03M2009: -$108.44M2010: -$63.59M2011: -$114.80M2015: $21.12M2016: -$112.11M2017: $174.15M2018: $602.91M2019: $345.63M2020: $35.89M2021: $30.80M2022: -$274.37M2023: -$307.51M2024: -$500.95M2025: -$268.58M-$268.58M2008Operating Cash Flow (USD)2025Fiscal YearOperating Cash FlowChange YoY2025-$268.58M+46.4%2024-$500.95M-62.9%2023-$307.51M-12.1%2022-$274.37M-990.8%2021$30.80M-14.2%2020$35.89M-89.6%2019$345.63M-42.7%2018$602.91M+246.2%2017$174.15M+255.3%2016-$112.11M-630.7%2015$21.12M—2011-$114.80M-80.5%2010-$63.59M+41.4%2009-$108.44M-151.1%2008$212.03M—Other metrics: RevenueCost of RevenueGross ProfitOperating IncomeNet IncomeEPS (Diluted)Total AssetsTotal LiabilitiesShareholders' EquityCash & EquivalentsCapital ExpendituresShares OutstandingDividends Per Share