Compare
Harmony Biosciences Holdings, Inc. vs ANI Pharmaceuticals Inc vs Ionis Pharmaceuticals Inc vs Madrigal Pharmaceuticals, Inc.
| Latest fiscal year | Harmony Biosciences Holdings, Inc. HRMY | ANI Pharmaceuticals Inc ANIP | Ionis Pharmaceuticals Inc IONS | Madrigal Pharmaceuticals, Inc. MDGL |
|---|---|---|---|---|
| Year ended | 2025-12-31 | 2025-12-31 | 2025-12-31 | 2025-12-31 |
| Revenue | $868.45M | $883.37M | $943.71M | $958.40M |
| Revenue growth (YoY) | +21.5% | +43.8% | +33.8% | +432.1% |
| Gross margin | 77.2% | n/a | n/a | n/a |
| Operating margin | 24.0% | 12.6% | -40.4% | -31.3% |
| Net margin | 18.3% | 8.9% | -40.4% | -30.1% |
| Net income | $158.69M | $78.34M | -$381.39M | -$288.28M |
| EPS (Diluted) | $2.71 | $3.32 | -$2.38 | -$12.85 |
| Operating cash flow | $348.20M | $185.22M | -$268.58M | -$189.55M |
| Free cash flow | $347.89M | $171.39M | -$320.03M | -$190.02M |
| Cash & equivalents | $752.50M | $285.58M | $372.26M | $198.69M |
| Total assets | $1.27B | $1.44B | $3.52B | $1.26B |
| Total liabilities | $401.41M | $899.65M | $3.03B | $656.90M |
| Shareholders' equity | $870.22M | $540.72M | $489.09M | $602.69M |
| Return on year-end equity | 18.2% | 14.5% | -78.0% | -47.8% |
| Shares outstanding | 57.73M | 22.49M | 163.30M | 22.84M |
Revenue, most recent five fiscal years
| Fiscal year | Harmony Biosciences Holdings, Inc. | ANI Pharmaceuticals Inc | Ionis Pharmaceuticals Inc | Madrigal Pharmaceuticals, Inc. |
|---|---|---|---|---|
| Latest | $868.45M Ended 2025-12-31 | $883.37M Ended 2025-12-31 | $943.71M Ended 2025-12-31 | $958.40M Ended 2025-12-31 |
| 1 year earlier | $714.73M Ended 2024-12-31 | $614.38M Ended 2024-12-31 | $705.14M Ended 2024-12-31 | $180.13M Ended 2024-12-31 |
| 2 years earlier | $582.02M Ended 2023-12-31 | $486.82M Ended 2023-12-31 | $787.65M Ended 2023-12-31 | $0 Ended 2023-12-31 |
| 3 years earlier | $437.86M Ended 2022-12-31 | $316.38M Ended 2022-12-31 | $587.37M Ended 2022-12-31 | $0 Ended 2022-12-31 |
| 4 years earlier | $305.44M Ended 2021-12-31 | $216.14M Ended 2021-12-31 | $810.46M Ended 2021-12-31 | $0 Ended 2021-12-31 |