TickerFacts.

Spyre Therapeutics, Inc. (SYRE): Operating Income

Annual figures by period end, from SEC filings.

-$209.56M
Year ended 2025-12-31
-$201.34M
Trailing 12 months to 2026-06-30
2014-12-31: -$8.90M2015-12-31: -$11.31M2016-12-31: -$21.91M2017-12-31: -$27.68M2018-12-31: -$45.46M2019-12-31: -$80.33M2020-12-31: -$81.48M2021-12-31: -$65.65M2022-12-31: -$84.78M2023-12-31: -$242.30M2024-12-31: -$208.57M2025-12-31: -$209.56M-$209.56M
2014-12-31 Operating Income (USD) 2025-12-31
Period endedOperating IncomeChange YoYSource filing
2025-12-31-$209.56Mn/m2026-02-19, From 2025-01-01
2024-12-31-$208.57Mn/m2026-02-19, From 2024-01-01
2023-12-31-$242.30Mn/m2026-02-19, From 2023-01-01
2022-12-31-$84.78Mn/m2025-02-27, From 2022-01-01
2021-12-31-$65.65Mn/m2024-11-18, From 2021-01-01
2020-12-31-$81.48Mn/m2023-03-02, From 2020-01-01
2019-12-31-$80.33Mn/m2022-03-08, From 2019-01-01
2018-12-31-$45.46Mn/m2021-03-18, From 2018-01-01
2017-12-31-$27.68Mn/m2020-02-24, From 2017-01-01
2016-12-31-$21.91Mn/m2019-03-07, From 2016-01-01
2015-12-31-$11.31Mn/m2018-03-13, From 2015-01-01
2014-12-31-$8.90Mn/a2017-03-23, From 2014-01-01

Operating Income at similar companies

Companies with the same SEC industry code (Pharmaceutical Preparations), reporting in the same currency, closest in revenue. Each shows its own latest fiscal year, so period ends differ.

CompanyYear endedOperating IncomeChange YoY
Spyre Therapeutics, Inc. (SYRE)2025-12-31-$209.56Mn/m
Abbott Laboratories (ABT)2025-12-31$8.05B+18.0%
TherapeuticsMD, Inc. (TXMD)2025-12-31-$4.39Mn/m
Nature's Sunshine Products Inc (NATR)2025-12-31$24.74M+23.1%
Provectus Biopharmaceuticals, Inc. (PVCT)2025-12-31-$5.29Mn/m
Lisata Therapeutics, Inc. (LSTA)2025-12-31-$18.21Mn/m
Heron Therapeutics, Inc. (HRTX)2025-12-31-$2.54Mn/m
Teva Pharmaceutical Industries Ltd (TEVA)2025-12-31$2.16Bn/m
Emmaus Life Sciences, Inc. (EMMA)2025-12-31$231.0Kn/m

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