A business in context

SYRE research notebook

Read the disclosures. Follow the relationships. Keep the dates in view.

Research JSON

Filing timeline

Download filings CSV

SEC submissions · retrieved 2026-10-22 · 8029 issuers; up to 32 recent company reports and 8 ownership-change filings per issuer

  1. 8-K · Current report

    Report date 2026-10-05 · 0001628280-26-065291 · Items 1.01,9.01

  2. 4 · Ownership change

    Report date 2026-10-01 · 0001636282-26-000119

  3. 4 · Ownership change

    Report date 2026-10-01 · 0001636282-26-000118

  4. 4 · Ownership change

    Report date 2026-09-30 · 0001636282-26-000117

  5. 8-K · Current report

    Report date 2026-09-08 · 0001636282-26-000113 · Items 7.01,8.01,9.01

  6. 4 · Ownership change

    Report date 2026-09-01 · 0001636282-26-000111

  7. 4 · Ownership change

    Report date 2026-09-01 · 0001636282-26-000109

  8. 4 · Ownership change

    Report date 2026-09-01 · 0001636282-26-000107

  9. 8-K · Current report

    Report date 2026-08-25 · 0001636282-26-000105 · Items 7.01,8.01,9.01

  10. 4 · Ownership change

    Report date 2026-08-07 · 0001636282-26-000102

  11. 4 · Ownership change

    Report date 2026-08-03 · 0001636282-26-000100

  12. 8-K · Current report

    Report date 2026-08-04 · 0001636282-26-000098 · Items 2.02,9.01

  13. 10-Q · Quarterly report

    Report date 2026-06-30 · 0001636282-26-000096

  14. 8-K · Current report

    Report date 2026-06-15 · 0001636282-26-000083 · Items 7.01,8.01,9.01

  15. 8-K · Current report

    Report date 2026-05-29 · 0001636282-26-000075 · Items 8.01,9.01

  16. 8-K · Current report

    Report date 2026-05-27 · 0001636282-26-000056 · Items 5.02,5.07,9.01

  17. 8-K · Current report

    Report date 2026-05-05 · 0001636282-26-000051 · Items 2.02,9.01

  18. 10-Q · Quarterly report

    Report date 2026-03-31 · 0001636282-26-000050

  19. 8-K · Current report

    Report date 2026-04-14 · 0001628280-26-025508 · Items 1.01,9.01

  20. 8-K · Current report

    Report date 2026-04-13 · 0001628280-26-024906 · Items 2.02,8.01

  21. 8-K · Current report

    Report date 2026-04-13 · 0001628280-26-024831 · Items 7.01,8.01,9.01

  22. DEF 14A · Proxy statement

    Report date 2026-05-27 · 0001636282-26-000039

  23. 8-K · Current report

    Report date 2026-02-19 · 0001636282-26-000022 · Items 2.02,9.01

  24. 10-K · Annual report

    Report date 2025-12-31 · 0001636282-26-000020

  25. 8-K · Current report

    Report date 2026-01-12 · 0001193125-26-009894 · Items 7.01,9.01

  26. 8-K · Current report

    Report date 2025-11-04 · 0001636282-25-000104 · Items 2.02,7.01,8.01,9.01

  27. 10-Q · Quarterly report

    Report date 2025-09-30 · 0001636282-25-000102

  28. 8-K · Current report

    Report date 2025-10-13 · 0001193125-25-240237 · Items 1.01,9.01

  29. 8-K · Current report

    Report date 2025-10-14 · 0001193125-25-237904 · Items 2.02

  30. 8-K · Current report

    Report date 2025-08-05 · 0001636282-25-000091 · Items 2.02,9.01

  31. 10-Q · Quarterly report

    Report date 2025-06-30 · 0001636282-25-000089

  32. 8-K · Current report

    Report date 2025-06-17 · 0001193125-25-141756 · Items 7.01,8.01,9.01

  33. 8-K · Current report

    Report date 2025-05-29 · 0001636282-25-000063 · Items 5.07,9.01

  34. 8-K · Current report

    Report date 2025-05-08 · 0001636282-25-000050 · Items 2.02,9.01

  35. 10-Q · Quarterly report

    Report date 2025-03-31 · 0001636282-25-000049

  36. DEF 14A · Proxy statement

    Report date 2025-05-29 · 0001636282-25-000038

  37. 8-K · Current report

    Report date 2025-02-28 · 0001193125-25-048423 · Items 4.01,9.01

  38. 8-K · Current report

    Report date 2025-02-27 · 0001636282-25-000022 · Items 2.02,9.01

  39. 10-K · Annual report

    Report date 2024-12-31 · 0001636282-25-000020

  40. 8-K · Current report

    Report date 2025-01-13 · 0001193125-25-005015 · Items 2.02,8.01,9.01

Reported insider transactions

Download transactions CSV

SEC insider transactions · retrieved 2026-10-15 · 2026 Q3: filings in this completed quarter; not a live transaction feed

Purchases and sales include open-market or private transactions. Grants, exercises and tax withholding are shown separately. Amendments and joint reports can overlap; rows are not a net-buying score. Prices retain the filing's units; consult its footnotes.

Transaction rows by code · counts, not monetary totals
Purchase: 0 transaction rows0PSale: 32 transaction rows32SGrant / award: 0 transaction rows0AExercise / conversion: 14 transaction rows14MTax / exercise payment: 0 transaction rows0FGift: 0 transaction rows0G
P · PurchaseS · SaleA · Grant / awardM · Exercise / conversionF · Tax / exercise paymentG · Gift

46 matching transaction rows.

Transaction / filedReporting ownerTypeSecuritySharesReported price
2026-09-02
2026-09-03
King-Jones Heidy
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock400.090.0
2026-09-02
2026-09-03
King-Jones Heidy
10b5-1 checkbox reported
M · Exercise / conversion
Acquired
Common Stock400.014.5
2026-09-02
2026-09-03
King-Jones Heidy
10b5-1 checkbox reported
M · Exercise / conversion
Disposed
Stock Option (Right to Buy)
Derivative security
400.00.0
2026-09-02
2026-09-03
Burrows Scott L
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock18232.089.35
2026-09-01
2026-09-03
King-Jones Heidy
10b5-1 checkbox reported
M · Exercise / conversion
Acquired
Common Stock27999.014.5
2026-09-01
2026-09-03
King-Jones Heidy
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock4845.086.4
2026-09-01
2026-09-03
King-Jones Heidy
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock16548.087.2
2026-09-01
2026-09-03
King-Jones Heidy
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock6206.088.17
2026-09-01
2026-09-03
King-Jones Heidy
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock400.089.38
2026-09-01
2026-09-03
King-Jones Heidy
10b5-1 checkbox reported
M · Exercise / conversion
Disposed
Stock Option (Right to Buy)
Derivative security
27999.00.0
2026-09-01
2026-09-03
Burrows Scott L
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock200.089.04
2026-09-01
2026-09-03
Burrows Scott L
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock2016.088.03
2026-09-01
2026-09-03
Burrows Scott L
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock900.086.25
2026-09-01
2026-09-03
Burrows Scott L
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock4384.087.11
2026-09-01
2026-09-03
Burrows Scott L
10b5-1 checkbox reported
M · Exercise / conversion
Acquired
Common Stock7500.014.5
2026-09-01
2026-09-03
Burrows Scott L
10b5-1 checkbox reported
M · Exercise / conversion
Disposed
Stock Option (Right to Buy)
Derivative security
7500.00.0
2026-09-01
2026-09-03
Turtle Cameron
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock8400.087.15
2026-09-01
2026-09-03
Turtle Cameron
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock2500.086.36
2026-09-01
2026-09-03
Turtle Cameron
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock400.089.07
2026-09-01
2026-09-03
Turtle Cameron
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock3700.088.06
2026-08-07
2026-08-10
Albers Jeffrey W.
10b5-1 checkbox reported
M · Exercise / conversion
Acquired
Common Stock5000.010.39
2026-08-07
2026-08-10
Albers Jeffrey W.
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock5000.0104.47
2026-08-07
2026-08-10
Albers Jeffrey W.
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock8000.0104.38
2026-08-07
2026-08-10
Albers Jeffrey W.
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock10000.0104.68
2026-08-07
2026-08-10
Albers Jeffrey W.
10b5-1 checkbox reported
M · Exercise / conversion
Disposed
Stock Option (Right to Buy)
Derivative security
5000.00.0
2026-08-03
2026-08-05
Burrows Scott L
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock2300.096.3
2026-08-03
2026-08-05
Burrows Scott L
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock5100.095.21
2026-08-03
2026-08-05
Burrows Scott L
10b5-1 checkbox reported
M · Exercise / conversion
Acquired
Common Stock7500.014.5
2026-08-03
2026-08-05
Burrows Scott L
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock100.097.1
2026-08-03
2026-08-05
Burrows Scott L
10b5-1 checkbox reported
M · Exercise / conversion
Disposed
Stock Option (Right to Buy)
Derivative security
7500.00.0
2026-08-03
2026-08-05
Turtle Cameron
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock800.093.97
2026-08-03
2026-08-05
Turtle Cameron
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock7157.095.1
2026-08-03
2026-08-05
Turtle Cameron
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock5635.095.93
2026-08-03
2026-08-05
Turtle Cameron
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock1392.096.82
2026-08-03
2026-08-05
Turtle Cameron
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock16.097.46
2026-07-01
2026-07-02
Burrows Scott L
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock5775.087.55
2026-07-01
2026-07-02
Burrows Scott L
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock1725.088.37
2026-07-01
2026-07-02
Burrows Scott L
10b5-1 checkbox reported
M · Exercise / conversion
Acquired
Common Stock7500.014.5
2026-07-01
2026-07-02
Burrows Scott L
10b5-1 checkbox reported
M · Exercise / conversion
Disposed
Stock Option (Right to Buy)
Derivative security
7500.00.0
2026-07-01
2026-07-02
Sloan Sheldon
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock1834.088.34
2026-07-01
2026-07-02
Sloan Sheldon
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock6500.087.52
2026-07-01
2026-07-02
Sloan Sheldon
10b5-1 checkbox reported
M · Exercise / conversion
Acquired
Common Stock8334.027.46
2026-07-01
2026-07-02
Sloan Sheldon
10b5-1 checkbox reported
M · Exercise / conversion
Disposed
Stock Option (Right to Buy)
Derivative security
8334.00.0
2026-07-01
2026-07-02
Turtle Cameron
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock4234.088.12
2026-07-01
2026-07-02
Turtle Cameron
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock590.088.91
2026-07-01
2026-07-02
Turtle Cameron
10b5-1 checkbox reported
S · Sale
Disposed
Common Stock10176.087.44

Identity & relationships

Wikidata structured data · retrieved 2026-10-15 · 1663 unambiguous CIK-linked entities; coverage is incomplete

These are sourced identity and relationship claims, with incomplete coverage. Headquarters locations do not describe sales, assets or operating exposure.

SEC issuer · 0001636282Spyre Therapeutics, Inc.

No parent relationship is available in this import; this is not proof of independence.

No verified LEI join available.

GLEIF legal entity reference data · retrieved 2026-10-15 · 1199 checked identities; 0 unavailable records

Search names and former names

View Wikidata identity and references ↗

  • Aeglea BioTherapeutics · alias · wikidata
  • Aeglea BioTherapeutics Inc. · alias · wikidata
  • Aeglea BioTherapeutics, Inc. · former SEC name · 2015-03-24 to 2023-11-24
Explore headquarters map ↗

Revenue in constant purchasing power

USD revenue expressed in 2026-09 consumer-price dollars. Each annual period uses a CPI-U average weighted by the days in its actual reporting interval. This is a purchasing-power comparison, not a company-specific price or volume measure.

Year endedReported USD revenueCPI-adjusted USD revenue
2024-12-31$0$0
2023-12-31$886.0K$979.7K
2022-12-31$2.33M$2.68M
2021-12-31$18.74M$23.30M
2020-12-31$0$0
2019-12-31$0$0
2018-12-31$3.89M$5.22M
2017-12-31$5.21M$7.15M

Bureau of Labor Statistics · retrieved 2026-10-22 · 9 selected series; gaps remain missing

Explore the CPI history ↗