Compare
Xenetic Biosciences, Inc. vs TherapeuticsMD, Inc. vs Upstream Bio, Inc. vs Cartesian Therapeutics, Inc.
| Latest fiscal year | Xenetic Biosciences, Inc. XBIO | TherapeuticsMD, Inc. TXMD | Upstream Bio, Inc. UPB | Cartesian Therapeutics, Inc. RNAC |
|---|---|---|---|---|
| Year ended | 2025-12-31 | 2025-12-31 | 2025-12-31 | 2025-12-31 |
| Revenue | $2.98M | $3.02M | $2.85M | $2.80M |
| Revenue growth (YoY) | +19.0% | +71.6% | +20.4% | -92.8% |
| Gross margin | n/a | n/a | n/a | n/a |
| Operating margin | -95.2% | -145.3% | n/m | n/m |
| Net margin | -90.1% | -18.8% | n/m | n/m |
| Net income | -$2.68M | -$569.0K | -$143.44M | -$130.30M |
| EPS (Diluted) | -$1.58 | -$0.05 | -$2.66 | -$5.02 |
| Operating cash flow | -$2.29M | $2.45M | -$133.28M | -$73.94M |
| Free cash flow | n/a | n/a | -$133.44M | -$79.39M |
| Cash & equivalents | n/a | n/a | $101.58M | $125.14M |
| Total assets | $8.36M | $37.66M | $353.77M | $296.41M |
| Total liabilities | $968.0K | $10.78M | $14.00M | $422.65M |
| Shareholders' equity | $7.40M | $26.88M | $339.77M | -$126.24M |
| Return on year-end equity | -36.2% | -2.1% | -42.2% | n/a |
| Shares outstanding | 2.29M | 11.57M | 54.24M | 26.01M |
Revenue, most recent five fiscal years
| Fiscal year | Xenetic Biosciences, Inc. | TherapeuticsMD, Inc. | Upstream Bio, Inc. | Cartesian Therapeutics, Inc. |
|---|---|---|---|---|
| Latest | $2.98M Ended 2025-12-31 | $3.02M Ended 2025-12-31 | $2.85M Ended 2025-12-31 | $2.80M Ended 2025-12-31 |
| 1 year earlier | $2.50M Ended 2024-12-31 | $1.76M Ended 2024-12-31 | $2.37M Ended 2024-12-31 | $38.91M Ended 2024-12-31 |
| 2 years earlier | $2.54M Ended 2023-12-31 | $1.30M Ended 2023-12-31 | $2.38M Ended 2023-12-31 | $26.00M Ended 2023-12-31 |
| 3 years earlier | $1.71M Ended 2022-12-31 | $69.96M Ended 2022-12-31 | n/a | n/a |
| 4 years earlier | $1.16M Ended 2021-12-31 | $2.57M Ended 2021-12-31 | n/a | n/a |