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Mineralys Therapeutics, Inc. vs Protagonist Therapeutics, Inc vs Immunome Inc. vs Wave Life Sciences, Inc.

Latest annual figures from SEC filings. Each company is shown for its own most recent fiscal year, so period ends can differ. Select a figure to see its full history.

Latest fiscal yearMineralys Therapeutics, Inc.
MLYS
Protagonist Therapeutics, Inc
PTGX
Immunome Inc.
IMNM
Wave Life Sciences, Inc.
WVE
Year ended2025-12-312025-12-312025-12-312025-12-31
Revenuen/a$46.02M$6.94M$42.73M
Revenue growth (YoY)n/a-89.4%-23.2%-60.5%
Gross marginn/an/an/an/a
Operating marginn/a-343.6%n/m-504.1%
Net marginn/a-282.8%n/m-478.3%
Net income-$154.65M-$130.15M-$212.39M-$204.38M
EPS (Diluted)-$2.29-$2.05-$2.43-$1.21
Operating cash flow-$142.42M$57.67M-$190.92M-$187.49M
Free cash flow-$142.43M$56.08M-$200.60M-$188.21M
Cash & equivalents$172.92M$128.39M$653.48M$602.07M
Total assets$661.81M$668.19M$683.19M$638.50M
Total liabilitiesn/a$53.48M$48.84M$112.27M
Shareholders' equity$646.69M$614.71M$634.34M$518.36M
Return on year-end equity-23.9%-21.2%-33.5%-39.4%
Shares outstanding81.54M62.58M113.13M187.66M

n/a means the company did not report that line under the concept TickerFacts maps, not that it is zero.

Revenue, most recent five fiscal years

Fiscal yearMineralys Therapeutics, Inc.Protagonist Therapeutics, IncImmunome Inc.Wave Life Sciences, Inc.
Latestn/a$46.02M
Ended 2025-12-31
$6.94M
Ended 2025-12-31
$42.73M
Ended 2025-12-31
1 year earliern/a$434.43M
Ended 2024-12-31
$9.04M
Ended 2024-12-31
$108.30M
Ended 2024-12-31
2 years earliern/a$60.00M
Ended 2023-12-31
$14.02M
Ended 2023-12-31
$113.31M
Ended 2023-12-31
3 years earliern/a$26.58M
Ended 2022-12-31
n/a$3.65M
Ended 2022-12-31
4 years earliern/a$27.36M
Ended 2021-12-31
n/a$40.96M
Ended 2021-12-31