Compare
Castle Biosciences Inc vs BillionToOne, Inc. vs Caris Life Sciences, Inc. vs Guardant Health, Inc.
| Latest fiscal year | Castle Biosciences Inc CSTL | BillionToOne, Inc. BLLN | Caris Life Sciences, Inc. CAI | Guardant Health, Inc. GH |
|---|---|---|---|---|
| Year ended | 2025-12-31 | 2025-12-31 | 2025-12-31 | 2025-12-31 |
| Revenue | $344.23M | $305.11M | $812.03M | $982.02M |
| Revenue growth (YoY) | +3.7% | +100.0% | +97.0% | +32.9% |
| Gross margin | 79.4% (computed) | 68.3% | n/a | 64.5% (computed) |
| Operating margin | -12.4% | 5.3% | 5.6% | -44.5% |
| Net margin | -7.0% | 2.4% | -8.4% | -42.4% |
| Net income | -$24.16M | $7.45M | -$68.09M | -$416.28M |
| EPS (Diluted) | -$0.83 | $0.14 | -$3.22 | -$3.32 |
| Operating cash flow | $64.35M | $24.59M | $83.16M | -$184.76M |
| Free cash flow | $28.33M | $15.71M | $66.89M | -$233.07M |
| Cash & equivalents | $116.73M | $495.98M | $796.27M | $378.20M |
| Total assets | $578.56M | $632.65M | $1.13B | $2.01B |
| Total liabilities | $107.68M | $152.55M | $548.36M | $2.11B |
| Shareholders' equity | $470.87M | $480.11M | $577.31M | -$99.31M |
| Return on year-end equity | -5.1% | 1.6% | -11.8% | n/a |
| Shares outstanding | 29.69M | n/a | 282.53M | 130.64M |
Revenue, most recent five fiscal years
| Fiscal year | Castle Biosciences Inc | BillionToOne, Inc. | Caris Life Sciences, Inc. | Guardant Health, Inc. |
|---|---|---|---|---|
| Latest | $344.23M Ended 2025-12-31 | $305.11M Ended 2025-12-31 | $812.03M Ended 2025-12-31 | $982.02M Ended 2025-12-31 |
| 1 year earlier | $332.07M Ended 2024-12-31 | $152.58M Ended 2024-12-31 | $412.26M Ended 2024-12-31 | $739.02M Ended 2024-12-31 |
| 2 years earlier | $219.79M Ended 2023-12-31 | $71.73M Ended 2023-12-31 | $306.13M Ended 2023-12-31 | $563.95M Ended 2023-12-31 |
| 3 years earlier | $137.04M Ended 2022-12-31 | n/a | n/a | $449.54M Ended 2022-12-31 |
| 4 years earlier | $94.08M Ended 2021-12-31 | n/a | n/a | $373.65M Ended 2021-12-31 |